Bee Venom is a complex mixture of proteins (enzymes and peptides) with unique pharmacological activities. he main enzymes in Bee Venom are hyaluronidase and phopholiphaseA. Peptides are proteins that possess specific biological activities. here are three major peptides found in Bee Venom: melittin, apamin, and peptide 401. Melitten and apamin stimulate the body's adrenal and pituitary systems to produce cortisol and natural steroids. Natually produced steroids do not produce the medical complications of synthetic steroids. Peptide 401 is a powerful anti immflamatory agent, found to be up to one hundred times more effective than cortisone when administered at equivalent dosages.